Vidross™ XG

Bioactive Glass Matrix

React. Regenerate. Remodel.

 

Vidross™ XG Putty is a Bioactive Synthetic Glass Matrix that combines bioactive calcium-phospho-silicate particulate with a synthetic, absorbable binder—providing an osteostimulative moldable graft material.

Simple & Efficient Handling

  • Ready to use, requires no preparation, and can be directly applied to the intended graft site
  • Highly malleable, easy to mold, and pack or graft directly into any defect
  • Available in MIS, Tray and Syringe configurations
  • More flowable MIS formulation for minimally invasive delivery

Bioglass 45S5

  • Cell Proliferation & Differentiation – 45S5 Bioactive Glass sitmulates growth and osteogenic differentiation of human primary osteoblasts1
  • Unique composition encourages the formation of hydroxyapatite layers on the surface which mimics bone composition
  • Osteostimulative properties make it an ideal material for bone tissue regeneration

Osteostimulation2

Bioactive Ion Release

  • Calcium and silicate ions are released at critical concentrations as the bioactive glass begins to dissolve

Cellular Stimulation

  • Ionic dissolution products interact with osteoblasts and osteogenic precursor cells, stimulating cellular activity associated with new bone formation

Upregulation of Osteogenic Gene Families

  • Growth factors, including IGF-II and VEGF
  • Transcription factors and cell-cycle regulators
  • Cell-surface antigens and receptors

Safe & Reliable

  • Provides a bone void filler that resorbs and is replaced with bone during the healing process
  • 99% Putty resorption after 8-12 months
  • 20+ years of Clinical Use
  • 2+ Millions implanted worldwide
  • 3+ year shelf life

 

1. Xynos, I.D., Hukkanen, M.V., Batten, J.J., Buttery, L.D.K, Hench, L.L., Polak, J.M. (2000). Bioglass 45S5 stimulates osteoblast turnover and enhances bone formation In vitro: Implications and applications
for bone tissue engineering. Calcif Tissue Int. 67(4), 321-9.

2. Hench LL, Gaisser DM. The Genetic Basis for Osteogenesis Stimulation by Controlled Release of Ionic Dissolution Products. Transactions of the Orthopedic Research Society, Annual Meeting, San Francisco, California, USA 2008 Mar (Vol. 1697)

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